Low affinity antibodies, by contrast, bind weakly to the antigen and often do not detect the antigen in-vivo or in assays.īecause antibodies can potentially be generated against millions of unique epitopes, the size of an organism’s genome would need to increase exponentially in order to code for every possible antigen-binding site. High affinity antibodies bind quickly to the antigen, permit greater sensitivity in assays and maintain this bond more readily under difficult conditions. Antibody affinity refers to the strength with which the epitope binds to an individual paratope ( antigen-binding site) on the antibody.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |